GSK-364735 (sodium)
GSK-364735 sodium (S/GSK-364735 sodium) is the sodium salt form of GSK-364735 (HY-16907) . GSK-364735 sodium is an antiretroviral, that inhibits the integrase of human immunodeficiency virus type 1 (HIV-1) with an IC50 of 7.8 nM[1].
Product Specifications
CAS Number
[863437-78-9]
Product Name Alternative
S/GSK-364735 (sodium)
UNSPSC
12352005
Target
HIV; HIV Integrase
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
O=C(C1=C(O)C2=C(C=C(CC3=CC=C(C=C3)F)C=N2)N(C)C1=O)NCCO.[Na]
Molecular Formula
C19H18FN3NaO4
Molecular Weight
394.35
References & Citations
[1]Garvey EP, et al., The naphthyridinone GSK364735 is a novel, potent human immunodeficiency virus type 1 integrase inhibitor and antiretroviral. Antimicrob Agents Chemother. 2008 Mar;52 (3) :901-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Curated Selection
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