Firsocostat (Standard)
Firsocostat (Standard) is the analytical standard of Firsocostat. This product is intended for research and analytical applications. Firsocostat (ND-630; GS-0976; NDI-010976) is an acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1 nM, respectively.
Product Specifications
CAS Number
[1434635-54-7]
UNSPSC
12352100
Target
Acetyl-CoA Carboxylase; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Smiles
O=C(C(C(C)=C(C1=NC=CO1)S2)=C2N3C[C@H](OC4CCOCC4)C5=C(OC)C=CC=C5)N(C(C)(C)C(O)=O)C3=O
Molecular Formula
C28H31N3O8S
Molecular Weight
569.63
References & Citations
[1]Harriman G, et al. Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats. Proc Natl Acad Sci U S A. 2016 Mar 29;113 (13) :E1796-805.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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