TSWV-IN-2

TSWV-IN-2 (Compound Z9) is an inhibitor of TSWV N protein, with an EC50 of 65.3 μg/mL against TSWV. TSWV-IN-2 has broad-spectrum antiviral activity against plant viruses. TSWV-IN-2 targets the TSWV N protein, interferes with the formation of condensates between the N protein and RNA, and inhibits the replication of viral ribonucleoproteins[1].

Product Specifications

UNSPSC

12352005

Target

Tomato Spotted Wilt Virus (TSWV)

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C1C(/C=C/C(N2CCN(C(SCCCN(C)C)=S)CC2)=O)=COC3=CC=CC=C31

Molecular Formula

C22H27N3O3S2

Molecular Weight

445.60

References & Citations

[1]Zan N, et al. Rational design of phytovirucide inhibiting nucleocapsid protein aggregation in tomato spotted wilt virus. Nat Commun. 2025 Feb 27;16 (1) :2034.