Ethanolamine-Thalidomide-4-OH
Ethanolamine-Thalidomide-4-OH is an E3 Ligase Ligand-Linker Conjugate composed of an CRBN ligand (HY-103596) and a linker (HY-Y0524), and can be used for synthesis of PROTACs (eg: PROTAC BTK Degrader-13 (HY-168963) ) [1].
Product Specifications
CAS Number
[1957235-61-8]
UNSPSC
12352211
Target
E1/E2/E3 Enzyme; E3 Ligase Ligand-Linker Conjugates
Related Pathways
Metabolic Enzyme/Protease; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
OCCNC1=C2C(C(N(C3C(NC(CC3)=O)=O)C2=O)=O)=CC=C1
Molecular Formula
C15H15N3O5
Molecular Weight
317.30
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
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