Antiparasitic agent-25

Antiparasitic agent-25 (Compounds 11) is an orally active antiparasitic agent. Antiparasitic agent-25 inhibits both parasite invasion and replication ability and has irreversible action against Toxoplasma gondii, significantly reducing the replication rate of Toxoplasma gondii with an IC50 value of 6.33 μM, and demonstrates low cytotoxicity with a CC50 value of 285 μM[1].

Product Specifications

UNSPSC

12352211

Target

Parasite

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

O=C(NC1=CC=C(OC2=CC=CC=C2)C=C1)CN3CCN(C(N4C5=CC=CC=C5)=NC6=C(C=CC=C6)C4=O)CC3

Molecular Formula

C32H29N5O3

Molecular Weight

531.60

References & Citations

[1]Deng Y, et al. Design, Synthesis, and Structure-Activity Relationship of 2- (Piperazin-1-yl) quinazolin-4 (3H) -one Derivatives as Active Agents against Toxoplasma gondii. J Agric Food Chem. 2025 Mar 12;73 (10) :6215-6230.