Pks13-IN-2
Pks13-IN-2 (Compound 43) is an orally active inhibitor of Pks13. Pks13-IN-2 exhibits inhibitory activity against Mycobacterium tuberculosis H37Rv, with a MIC of 0.8-1.8 μM. Pks13-IN-2 shows good metabolic stability in mouse liver microsomes and hepatocytes. Pks13-IN-2 can be used for tuberculosis research[1].
Product Specifications
UNSPSC
12352211
Target
Bacterial
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
CC1=NOC(C2=C(NC(C3=C(F)C(F)=C(F)C(F)=C3F)=O)OC(C)=N2)=N1
Molecular Formula
C14H7F5N4O3
Molecular Weight
374.22
References & Citations
[1]Green SR, et al. Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of Mycobacterium tuberculosis. ACS Infect Dis. 2025 Feb 27.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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