ABCB1-IN-4
ABCB1-IN-4 (Compound C6z) is an orally active and potent dual α-amylase and α-glucosidase inhibitor with IC50 values of 1.63 μM and 0.14 μM, respectively. ABCB1-IN-4 is promising for research of diabetes[1].
Product Specifications
CAS Number
[1500779-21-4]
UNSPSC
12352005
Target
Amylases; Glycosidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
CNC1=NN=C(S1)CN2C3=C(C=CC=C3)C4=C2C=CC=C4
Molecular Formula
C16H14N4S
Molecular Weight
294.37
References & Citations
[1]Çapan İ, et al. Novel carbazole-thiadiazole derivatives as α-amylase and α-glucosidase inhibitors: Design, biological evaluation, and computational insights. Bioorg Chem. 2025 Feb 12;157:108243.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Glucosidase
Curated Selection
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