CCOE-5

CCOE-5 is a chalcone compound with antiplasmodial activity, showing an IC50 of 1.4 μg/mL against P. falciparum (3D7), and an IC50 of less than 5 μg/mL against P. falciparum (INDO) . CCOE-5 holds promise for research in the field of anti-infective therapies[1].

Product Specifications

UNSPSC

12352005

Target

Parasite

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

COC1=CC=C(C=C1)C(/C=C/C2=CC=CC=C2)=N\OC3=CC=C(C=C3)C(/C=C/C4=CC(OC)=C(C(OC)=C4)OC)=O

Molecular Formula

C34H31NO6

Molecular Weight

549.61

References & Citations

[1]Chaudhary R, et al. Oxime functionalized Chalcones: Unveiling a new class of Chalcones with potent Antiplasmodial activity against blood-stages of Plasmodium falciparum in culture. Bioorg Med Chem Lett. 2025 Feb 18;121:130143.