Antibiofilm agent prodrug 1
Antibiofilm agent prodrug 1 (Compound 5c) exhibits antibacterial activity through inhibition of biofilm formation and iron uptake. Antibiofilm agent prodrug 1 inhibits P. aeruginosa PAO1 with a MIC of 1.07 μM. Antibiofilm agent prodrug 1 exhibits anti-infectious efficacy in C. elegans with improved survival rate[1].
Product Specifications
UNSPSC
12352101
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
FC1=C(C=C(N(C)C=C(C(OCC2=CC(C(O)=CN2C)=O)=O)C3=O)C3=C1)N4CCNCC4
Molecular Formula
C22H23FN4O5
Molecular Weight
442.44
References & Citations
[1]Wang Y Y, et al. Discovery of 3-hydroxypyridin-4 (1H) -ones ester of ciprofloxacin as prodrug to combat biofilm-associated Pseudomonas aeruginosa[J]. European Journal of Medicinal Chemistry, 2025: 117396.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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