HR-568
HR-568 exhibits broad-spectrum anti-enterovirus activity. HR-568 inhibits enterovirus species EV-A71, E30 and CVA24 in cell MRC-5 with EC50 of 1.53 μM, 0.4 μM and 1.22 μM. HR-568 targets hydrophobic canyon pocket on the enterovirus capsid protein, and inhibits the virus replication[1].
Product Specifications
UNSPSC
12352005
Target
Enterovirus
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
C1(SCC2=CC=C(N3N=CN=C3)C=C2)=NC=C(C4=CC=C5C=CC=CC5=C4)C=C1
Molecular Formula
C24H18N4S
Molecular Weight
394.49
References & Citations
[1]Roux H, et al., Design and synthesis of novel thioether analogs as promising antiviral agents: In vitro activity against enteroviruses of interest. Eur J Med Chem. 2025 Feb 14;288:117395.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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