NSD-IN-4
NSD-IN-4 (Compound A8) is a potent and an orally active NSD3 inhibitor. NSD-IN-4 induces Apoptosis in a dose-dependent manner. NSD-IN-4 exhibits significant antitumor effects against lung squamous carcinoma[1].
Product Specifications
UNSPSC
12352211
Target
Apoptosis; Histone Methyltransferase
Related Pathways
Apoptosis; Epigenetics
Field of Research
Cancer
Smiles
O=C(C(Cl)=C1NCCC2=CC=CC(F)=C2)C3=C(N=CC=C3)C1=O
Molecular Formula
C17H12ClFN2O2
Molecular Weight
330.74
References & Citations
[1]Xiu S, et al. Design, Synthesis, and Antitumor Activity of NSDs Inhibitors Targeting Lung Squamous Cell Carcinoma. European Journal of Medicinal Chemistry, 2025: 117388.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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