E3 Ligase Ligand-linker Conjugate 168
E3 Ligase Ligand-linker Conjugate 168 is a conjugate composed of E3 ligase Cereblon ligand (HY-W249500) and a linker. E3 Ligase Ligand-linker Conjugate 168 can be used for synthesis of PROTAC c-Met degrader-3 (HY-168910) [1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C1NC(CCN1C2=CC(C(N3CCC4(CC3)CCN(CC4)C(CBr)=O)=O)=CC=C2OC)=O
Molecular Formula
C23H29BrN4O5
Molecular Weight
521.40
References & Citations
[1]Qiu X, et al., Rational Design, Synthesis, and Biological Evaluation of Novel c-Met Degraders for Lung Cancer Therapy. J Med Chem. 2025 Feb 13;68 (3) :2815-2839.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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