MRK-952
MRK-952, a chemical probe, is a NUDIX hydrolase inhibitor. NUDIX enzymes are involved in cellular metabolism and homeostasis, as well as mRNA processing[1].
Product Specifications
UNSPSC
12352101
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
CN1C=NC2=C1C(N3CC[C@@]4(CCN(C4)C5=CC(Cl)=C(C=C5)C(F)(F)F)C3)=NC=N2
Molecular Formula
C20H20ClF3N6
Molecular Weight
436.86
References & Citations
[1]Carreras-Puigvert J, et al. A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family. Nat Commun. 2017 Nov 16;8 (1) :1541.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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