BI-113823
BI-113823, a chemical probe, is an orally active and selective bradykinin B1 receptor antagonist. BI-113823 can reduce complete Freund's adjuvant (HY-153808) -induced mechanical hyperalgesia in rats. BI-113823 can be used for the research of chronic inflammatory pain[1].
Product Specifications
CAS Number
[1119282-90-4]
UNSPSC
12352005
Target
Bradykinin Receptor
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
O=S(N(C)CCOCC(N([C@@H]1C[C@H](N2CCN(CC2)C)CCC1)C)=O)(C3=C(C=C(C=C3C)OC)C)=O
Molecular Formula
C26H44N4O5S
Molecular Weight
524.72
References & Citations
[1]Schuelert N, et al. The bradykinin B1 receptor antagonist BI113823 reverses inflammatory hyperalgesia by desensitization of peripheral and spinal neurons. Eur J Pain. 2015 Jan;19 (1) :132-42.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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