SGC-CAMKK2-1
SGC-CAMKK2-1, a chemical probe, is the selective, inhibitor for calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) with an IC50 of 30 nM. SGC-CAMKK2-1 inhibits AMPK phosphorylation in cell C4-2 with an IC50 of 1.6 μM[1].
Product Specifications
CAS Number
2561494-76-4
UNSPSC
12352005
Target
Calmodulin
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
98.80
Solubility
DMSO : 40 mg/mL (ultrasonic; warming)
Smiles
O=C(C1=C(C2CCCC2)C=C(C3=COC4=NC=C(C5=CC(C)=CC=C5)C=C43)C=C1)O
Molecular Formula
C26H23NO3
Molecular Weight
397.47
References & Citations
[1]Wells C, et al., SGC-CAMKK2-1: A Chemical Probe for CAMKK2. Cells. 2023 Jan 11;12 (2) :287.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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