BI-1942

BI-1942, a chemical probe, is a chymase inhibitor and has an IC50 of 0.4 nM for human chymase. BI-1942 can be used in the research of ophthalmic diseases[1].

Product Specifications

CAS Number

[1236524-95-0]

UNSPSC

12352005

Target

Proteasome

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Smiles

CN1C2=CC(C)=CC(C)=C2C(CN3C4=CC=CN=C4C(N(C3=O)[C@H](CC)CC(O)=O)=O)=C1

Molecular Formula

C24H26N4O4

Molecular Weight

434.49

References & Citations

[1]Abbe P, et al. Metadata analysis of Boehringer Ingelheim's opnMe database reveals the potential of BI-1942, a chymase inhibitor, for ophthalmic indications repurposing. Investigative Ophthalmology & Visual Science, 2024, 65 (7) : 6126-6126.