Hck-IN-2
Hck-IN-2 (Compound 8e) is an HCK inhibitor. Hck-IN-2 is cytotoxic to tumor cells, with IC50 values of 19.58 μM and 1.42 μM against MDA-MB231 and MCF-7, respectively. Hck-IN-2 has anti-tumor activity[1].
Product Specifications
UNSPSC
12352005
Target
Src
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
CC1=NN(C2=CC=CC=C2)C3=NC(C4=CC=C(F)C=C4)=CC(OCC5=CN([C@H]6[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](COC(C)=O)O6)N=N5)=C31
Molecular Formula
C36H35FN6O10
Molecular Weight
730.70
References & Citations
[1]Verma N, et al. Molecular Design, Synthesis and Anti-cancer Activity of Novel Pyrazolo[3,4-b]pyridine-based Glycohybrid Molecules. Bioorg Chem. 2025 Mar;156:108161.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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