Anticancer agent 263

Anticancer agent 263 (compound 7) is a potent anticancer agent. Anticancer agent 263 binds to the G-quadruplex DNA (G4) sequence 22-mer Pu22, a mimic of c-Myc DNA. Anticancer agent 263 is a structure modulator, showcasing a significant enhancement in protein α-helix formation and the capability to form supramolecular network. Anticancer agent 263 shows no cytotoxicity[1].

Product Specifications

UNSPSC

12352211

Target

C-Myc

Related Pathways

Apoptosis

Field of Research

Cancer

Smiles

CC1(OC(C(C(NCCO)=O)=C1CC[C@@H](C(O)=O)N)=O)C

Molecular Formula

C13H20N2O6

Molecular Weight

300.31

References & Citations

[1]Hayarpi Simonyan, et al. Exploring the binding of c-Myc G-quadruplex and the structural impact of synthetic non-proteinogenic amino acids on serum albumins: implications for potential intrinsic c-Myc-associated anticancer activity and drug delivery systems. Molecular Therapy:Nucleic Acid. 2025.|[2]Hayarpi Simonyan, et al. Exploring the binding of c-Myc G-quadruplex and the structural impact of synthetic non-proteinogenic amino acids on serum albumins: implications for potential intrinsic c-Myc-associated anticancer activity and drug delivery systems. Molecular Therapy:Nucleic Acid. 2025.