ZSH-512
ZSH-512 is a potent RARγ inhibitor. ZSH-512 shows antiproliferation activity. ZSH-512 induces apoptosis. ZSH-512 decreases CD133, NANOG, SOX2, and EPCAM protein expression. ZSH-512 shows anticancer activity. ZSH-512 has the potential for the research of colorectal cancer[1].
Product Specifications
CAS Number
2923210-02-8
UNSPSC
12352005
Target
Apoptosis; RAR/RXR
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
CCOC(C1=CN=C(N=C1N)C#CC2=CC3=C(S(CCC3(C)C)=O)C=C2)=O
Molecular Formula
C20H21N3O3S
Molecular Weight
383.46
References & Citations
[1]Suyao Li, et al. Novel cancer stem cell targeted retinoid ZSH-512 impedes colorectal cancer progress via KDM3A mediated epigenetic reprogramming. ScienceDirect. 2025
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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