PKM2 modulator 2

PKM2 modulator 2 (compound C599) is a potent PKM2 inhibitor. PKM2 modulator 2 shows antiproliferative activity. PKM2 modulator 2 induces apoptosis. PKM2 modulator 2 has the potential for the research of glioblastoma[1].

Product Specifications

CAS Number

[1356760-50-3]

UNSPSC

12352101

Target

Apoptosis; Pyruvate Kinase

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

FC(C=C1)=CC=C1OCC(O2)=NN=C2C3=CC4=C(N=C3)ON=C4C5=CC=CC=C5

Molecular Formula

C21H13FN4O3

Molecular Weight

388.35

References & Citations

[1]Maia Cabrera, et al. CADD-based discovery of novel oligomeric modulators of PKM2 with antitumor activity in aggressive human glioblastoma models. ScienceDirect. 2025.