PKM2 modulator 2
PKM2 modulator 2 (compound C599) is a potent PKM2 inhibitor. PKM2 modulator 2 shows antiproliferative activity. PKM2 modulator 2 induces apoptosis. PKM2 modulator 2 has the potential for the research of glioblastoma[1].
Product Specifications
CAS Number
[1356760-50-3]
UNSPSC
12352101
Target
Apoptosis; Pyruvate Kinase
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
FC(C=C1)=CC=C1OCC(O2)=NN=C2C3=CC4=C(N=C3)ON=C4C5=CC=CC=C5
Molecular Formula
C21H13FN4O3
Molecular Weight
388.35
References & Citations
[1]Maia Cabrera, et al. CADD-based discovery of novel oligomeric modulators of PKM2 with antitumor activity in aggressive human glioblastoma models. ScienceDirect. 2025.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168883/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1474875-01 0.02 mg (E-Coli)
Recombinant Nocardia farcinica Octanoyltransferase (lipB)
Ask
View Details 
MBS1474875-02 0.1 mg (E-Coli)
Recombinant Nocardia farcinica Octanoyltransferase (lipB)
Ask
View Details MBS1474875-03 0.02 mg (Yeast)
Recombinant Nocardia farcinica Octanoyltransferase (lipB)
Ask
View Details 
MBS1474875-04 0.1 mg (Yeast)
Recombinant Nocardia farcinica Octanoyltransferase (lipB)
Ask
View Details 
MBS1474875-05 0.02 mg (Baculovirus)
Recombinant Nocardia farcinica Octanoyltransferase (lipB)
Ask
View Details