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PKM2 modulator 2

PKM2 modulator 2 (compound C599) is a potent PKM2 inhibitor. PKM2 modulator 2 shows antiproliferative activity. PKM2 modulator 2 induces apoptosis. PKM2 modulator 2 has the potential for the research of glioblastoma[1].

Product Specifications

CAS Number

1356760-50-3

UNSPSC

12352101

Target

Apoptosis; Pyruvate Kinase

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

FC(C=C1)=CC=C1OCC(O2)=NN=C2C3=CC4=C(N=C3)ON=C4C5=CC=CC=C5

Molecular Formula

C21H13FN4O3

Molecular Weight

388.35

References & Citations

[1]Maia Cabrera, et al. CADD-based discovery of novel oligomeric modulators of PKM2 with antitumor activity in aggressive human glioblastoma models. ScienceDirect. 2025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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