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EP652

EP652 (compound 56) potently inhibits the enzymatic activity of METTL3, with the IC50s of 2 nM, [1].

Product Specifications

CAS Number

3050819-22-9

UNSPSC

12352211

Target

METTL3

Related Pathways

Epigenetics

Field of Research

Cancer

Smiles

C[C@H](N1C=CC(N2CCC[C@H](C2)NCC3CC3)=CC1=O)N4C=C(N=N4)C5=CC(N(C)C)=CN=C5

Molecular Formula

C25H34N8O

Molecular Weight

462.59

References & Citations

[1]Guillaume Dutheuil, et al. Discovery, Optimization, and Preclinical Pharmacology of EP652, a METTL3 Inhibitor with Efficacy in Liquid and Solid Tumor Models. J Med Chem. 2025 Jan 30.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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