EP652
EP652 (compound 56) potently inhibits the enzymatic activity of METTL3, with the IC50s of 2 nM, [1].
Product Specifications
CAS Number
[3050819-22-9]
UNSPSC
12352211
Target
METTL3
Related Pathways
Epigenetics
Field of Research
Cancer
Smiles
C[C@H](N1C=CC(N2CCC[C@H](C2)NCC3CC3)=CC1=O)N4C=C(N=N4)C5=CC(N(C)C)=CN=C5
Molecular Formula
C25H34N8O
Molecular Weight
462.59
References & Citations
[1]Guillaume Dutheuil, et al. Discovery, Optimization, and Preclinical Pharmacology of EP652, a METTL3 Inhibitor with Efficacy in Liquid and Solid Tumor Models. J Med Chem. 2025 Jan 30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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