API32
API32 is a potent Pin1 inhibitor. API32 interactes with the Pin1 PPIase domain. API32 inhibits cell proliferation and migration. API32 has the potential for the research of hepatocellular carcinoma (HCC) [1].
Product Specifications
CAS Number
[162320-41-4]
UNSPSC
12352005
Target
PIN1
Related Pathways
PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
NC1=NC2=C(N=CN2)C(OCC3=CC=C(OCO4)C4=C3)=N1
Molecular Formula
C13H11N5O3
Molecular Weight
285.26
References & Citations
[1]Pu W, et al. Structure-Guided Optimization and Preclinical Evaluation of 6-O-Benzylguanine-Based Pin1 Inhibitor for Hepatocellular Carcinoma Treatment. J Med Chem. 2025 Feb 13;68 (3) :2869-2889.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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