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E3 Ligase Ligand-linker Conjugate 161

E3 Ligase Ligand-linker Conjugate 161 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 161 can be used to synthesize Tamoxifen-PEG-Clozapine (HY-168869) [1].

Product Specifications

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

CN(C(CCC(NCCOCCOCCOCCN1CCN(CC1)C2=NC3=CC(Cl)=CC=C3NC4=CC=CC=C42)=O)=O)CCO

Molecular Formula

C32H45ClN6O6

Molecular Weight

645.19

References & Citations

[1]Takano R, Ohoka N, Kurohara T, et al. Clozapine as an E3 Ligand for PROTAC Technology[J]. ACS Medicinal Chemistry Letters, 2025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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