TBC-1
TBC-1 is a chlorophyll-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT) . TBC-1 efficiently generats Type-I ROS and endoplasmic reticulum targeting ability. TBC-1 shows biocompatibility and PDT efficiency in vitro under both normoxia and hypoxia[1].
Product Specifications
CAS Number
[2522115-48-4]
UNSPSC
12352101
Target
Photosensitizer; Reactive Oxygen Species (ROS)
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
BrC1=CC=C2C(CN3C4=C(CN2C3)C=C(/C=C/C(C5=CC6=C(OC5=O)C=C(C=C6)N(CC)CC)=O)C=C4)=C1
Molecular Formula
C31H28BrN3O3
Molecular Weight
570.48
References & Citations
[1]Rui Yuan, et al. Tröger’s Base as a Potential Bridge to Type-I Photosensitizers: Mechanism and Antitumor Applications. J Med Chem. 2025 Jan 7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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