Antibacterial agent 261
Antibacterial agent 261 (compound 43) is a potent inhibitor of peptidomimetic peptide deformylase (PDF), with IC50 of 2.5 and 10.6 nM for S. aureus and E. coli, respectively[1].
Product Specifications
CAS Number
3036109-97-1
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C([C@H](CCCC)CN(C=O)O)N1CCC[C@H]1C2=NN=C(C3=CC=CS3)S2
Molecular Formula
C18H24N4O3S2
Molecular Weight
408.54
References & Citations
[1]Shouning Yang, et al. Design, Synthesis, and Biological Evaluation of 1,3,4-Thiadiazole Derivatives as Novel Potent Peptide Deformylase Inhibitors for Combating Drug-Resistant Gram-Positive and -Negative Bacteria. J Med Chem. 2025 Jan 7. doi: 10.1021/acs.jmedchem.4c02177
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC471003-100 1x 100 µL
Mucin 5AC (MUC5AC) (58M1), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC472853-500 1x 500 µL
CD54 / ICAM-1 (15.2), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC470745-100 1x 100 µL
CD45 / LCA (2B11 + PD7/26), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC942556-100 1x 100 µL
Spectrin Alpha 1 (Erythrocyte Marker) (rSPTA1/1833), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC941219-500 1x 500 µL
Cytokeratin 8 (B22.1), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details