MTDH-SND1 blocker 2
MTDH-SND1 blocker 2 (compound C19) is a potent MTDH-SND1 blocker with an IC50 value of 487 nM. MTDH-SND1 blocker 2 binds to the SND1 protein with a Kd value of 279 nM. MTDH-SND1 blocker 2 degrades SND1 protein. MTDH-SND1 blocker 2 shows antiproliferative activity and induces apoptosis. MTDH-SND1 blocker 2 has the potential for the research of breast cancer[1].
Product Specifications
CAS Number
3052204-80-2
UNSPSC
12352101
Target
Apoptosis
Related Pathways
Apoptosis
Field of Research
Cancer
Purity
99.51
Solubility
DMSO : 12.5 mg/mL (ultrasonic)
Smiles
FC1=CC(C=CC=N2)=C2C(NS(C3=C(N=CC=C4)C4=CC=C3)(=O)=O)=C1
Molecular Formula
C18H12FN3O2S
Molecular Weight
353.37
References & Citations
[1]Shen H, et al. Discovery of Novel Small-Molecule Inhibitors Disrupting the MTDH-SND1 Protein-Protein Interaction. J Med Chem. 2025 Jan 10.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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