Resolvin D2 n-3 DPA
Resolvin D2 n-3 DPA is a specialized proresolving mediator (SPM) . Resolvin D2 n-3 DPA (1 nM) can reduce the chemotaxis and adhesion of human neutrophils induced by TNF-α. Resolvin D2 n-3 DPA (100 ng/mouse; intravenous injection) can reduce neutrophil infiltration in the peritoneum and the levels of IL-6 and the chemokine (C-C motif) ligand 2 (CCL2) in a mouse model of inflammation induced by zinc oxide[1].
Product Specifications
CAS Number
[2093111-29-4]
UNSPSC
12352211
Target
Interleukin Related; TNF Receptor
Related Pathways
Apoptosis; Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
CC/C=C\C[C@H](O)[C@H](O)/C=C/C=C/C=C\C=C\[C@@H](O)CCCCCC(O)=O
Molecular Formula
C22H34O5
Molecular Weight
378.50
References & Citations
[1]Dalli J, et al. Novel n-3 immunoresolvents: structures and actions. Sci Rep. 2013;3:1940.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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