LY433771
LY433771 (LSN433771) (Compound 8) is a type X secretory phospholipase A2 (sPLA2) inhibitor with an IC50 value of 3 nM, which can be used in the study of cardiovascular diseases[1][2].
Product Specifications
CAS Number
[220862-64-6]
Product Name Alternative
LSN433771
UNSPSC
12352211
Target
Phospholipase
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Purity
99.8
Solubility
DMSO : 3 mg/mL (ultrasonic; warming)
Smiles
O=C(C1=CC=CC2=C1C3=C(N2CC4CCCCC4)C=CC=C3OCC(O)=O)N
Molecular Formula
C22H24N2O4
Molecular Weight
380.44
References & Citations
[1]Takashi Ono, et al. V TYPE AND/OR X TYPE sPLA2 INHIBITORS. Patent, WO2001026653, 2001-04-19.|[2]Magrioti V, Kokotos G. Phospholipase A2 inhibitors as potential therapeutic agents for the treatment of inflammatory diseases[J]. Expert opinion on therapeutic patents, 2010, 20 (1) : 1-18.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Phospholipase A
Available Sizes
Curated Selection
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