α-Amylase-IN-12
α-Amylase-IN-12 (Compound 5e) is an α-amylase inhibitor (IC50: 0.15 mM) with a mixed inhibition. α-Amylase-IN-12 has an IC50 of 9.40 mM against α-glucosidase. α-Amylase-IN-12 promotes glucose uptake in yeast cells and exhibits significant antiglycation activity at high concentrations. α-Amylase-IN-12 can be used for the research of diabetes[1].
Product Specifications
CAS Number
[1799667-33-6]
UNSPSC
12352005
Target
Amylases; Glycosidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
O=C(OC(C1=CC=CC=C1)=N/2)C2=C\C3=CC=C(O)C(O)=C3
Molecular Formula
C16H11NO4
Molecular Weight
281.26
References & Citations
[1]Jayasinghe R N, et al. Evaluation of In Silico and In Vitro Antidiabetic Properties of 4- (Hydroxysubstituted Arylidene) -2-Phenyloxazol-5 (4 H) -one Derivatives. ACS Omega, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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