OBI-992 drug-linker
OBI-992 drug-linker is a drug-linker conjugate composed of a TOP I inhibitor Exatecan and a linker. OBI-992 drug-linker exhibits antitumor property in mouse models and can be used for synthesis of ADC OBI-992[1].
Product Specifications
CAS Number
3039487-10-7
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
96.64
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C=CC1=O)N1CC2CCC(C(N[C@@H](CCC(N[C@H](C(N[C@H](C(NC3=CC=C(COC(N[C@H]4CCC5=C6C4=C7C(C(N8C7)=CC([C@](CC)(O)C(OC9)=O)=C9C8=O)=NC6=CC(F)=C5C)=O)C=C3)=O)C)=O)C(C)C)=O)C(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)CC2
Molecular Formula
C106H162FN9O37
Molecular Weight
2173.46
References & Citations
[1]Li WF, et al., OBI-992, a Novel TROP2-Targeted Antibody-Drug Conjugate, Demonstrates Antitumor Activity in Multiple Cancer Models. Mol Cancer Ther. 2025 Feb 4;24 (2) :163-175.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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