13-TP prodrug

13-TP prodrug (compound 15) is a potent and orally active anti-SARS-CoV-2 agent. 13-TP prodrug shows cytotoxicity. 13-TP prodrug decreases the SARS-CoV-2 N protein expression. 13-TP prodrug shows antiviral activity[1].

Product Specifications

UNSPSC

12352005

Target

SARS-CoV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

C[C@H](C(OC(C)C)=O)N[P@@](OC1=CC=CC=C1)(OC[C@@H]2[C@@H](O)[C@](F)(CF)[C@H](N3C=NC4=C3N=C(N=C4NC)N)O2)=O.O=S(O)(O)=O.[0.5]

Molecular Formula

C24H32F2N7O7P.0.5H2O4S

Molecular Weight

648.69

References & Citations

[1]Liang L, et al. Discovery of a 2'-α-Fluoro-2'-β-C- (fluoromethyl) Purine Nucleotide Prodrug as a Potential Oral Anti-SARS-CoV-2 Agent. J Med Chem. 2025 Jan 23;68 (2) :1994-2007.