AAL-149
AAL-149 is a FTY720 analog and TRPM7 inhibitor (IC50 = 1.081 μM) with multimodal anti-inflammatory effects and without targeting S1P receptors. AAL-149 can be utilized in anti-inflammatory research[1].
Product Specifications
CAS Number
177258-60-5
UNSPSC
12352005
Target
TRP Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Inflammation/Immunology
Smiles
N[C@@](CO)(C)CCC1=CC=C(OCCCCCCC)C=C1
Molecular Formula
C18H31NO2
Molecular Weight
293.44
References & Citations
[1]Busey GW, et al. Analogs of FTY720 inhibit TRPM7 but not S1PRs and exert multimodal anti-inflammatory effects. J Gen Physiol. 2024 Jan 1;156 (1) :e202313419.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TRPM8
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