AAL-149

AAL-149 is a FTY720 (HY-12005) analog and TRPM7 inhibitor (IC50 = 1.081 μM) with multimodal anti-inflammatory effects and without targeting S1P receptors. AAL-149 can be utilized in anti-inflammatory research[1].

Product Specifications

CAS Number

[177258-60-5]

UNSPSC

12352005

Target

TRP Channel

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Inflammation/Immunology

Smiles

N[C@@](CO)(C)CCC1=CC=C(OCCCCCCC)C=C1

Molecular Formula

C18H31NO2

Molecular Weight

293.44

References & Citations

[1]Busey GW, et al. Analogs of FTY720 inhibit TRPM7 but not S1PRs and exert multimodal anti-inflammatory effects. J Gen Physiol. 2024 Jan 1;156 (1) :e202313419.