Y16526
Y16526 is a potent inhibitor of CBP/p300 bromodomain , with the IC50 of 0.03 μM. Y16524 has the potential for the research of acute myeloid leukemia (AML) [1].
Product Specifications
UNSPSC
12352005
Target
Epigenetic Reader Domain
Related Pathways
Epigenetics
Field of Research
Cancer
Smiles
COC1=CC=C(N([C@H](C2=NC(C3=CC=C(ON=C4C)C4=C3)=CN2C[C@H](C)N5CCOCC5)CCC6)C6=O)C=C1F
Molecular Formula
C30H34FN5O4
Molecular Weight
547.62
References & Citations
[1]Jian-Kang Hu, et al. Discovery of 5-imidazole-3-methylbenz[d]isoxazole derivatives as potent and selective CBP/p300 bromodomain inhibitors for the treatment of acute myeloid leukemia. Acta Pharmacol Sin. 2025 Jan 31.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
302552-HRP 200 µL
Med15 (Mediator of RNA Polymerase II Transcription Subunit 15, Mediator Complex Subunit 15, Positive Cofactor 2 glutamine/Q-rich-Associated Protein, PC2 glutamine/Q-rich-Associated Protein, mPcqap, Med15, Pcqap) (HRP) discontinued
Ask
View Details 
