Y16524
Y16524 is a potent inhibitor of CBP/p300 bromodomain , with the IC50 of 0.01 μM. Y16524 has the potential for the research of acute myeloid leukemia (AML) [1].
Product Specifications
UNSPSC
12352005
Target
Epigenetic Reader Domain
Related Pathways
Epigenetics
Field of Research
Cancer
Smiles
COC1=CC=C(N([C@H](C2=NC(C3=CC=C(ON=C4C)C4=C3)=CN2C[C@H](C)N5CCOCC5)CCC6)C6=O)C=C1Cl
Molecular Formula
C30H34ClN5O4
Molecular Weight
564.08
References & Citations
[1]Jian-Kang Hu, et al. Discovery of 5-imidazole-3-methylbenz[d]isoxazole derivatives as potent and selective CBP/p300 bromodomain inhibitors for the treatment of acute myeloid leukemia. Acta Pharmacol Sin. 2025 Jan 31.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168463/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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