DBAZ2B
DBAZ2B is a BAZ2B PROTAC degrader, with a DC50 of 19 nM[1]. (Pink: BAZ2A/B ligand ; Black: linker (HY-168450) ; Blue: VHL Ligand (HY-125905) )
Product Specifications
CAS Number
3104449-58-0
UNSPSC
12352005
Target
Epigenetic Reader Domain; PROTACs
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC1=C(SC=N1)C2=CC(OC[C@@H]3CC[C@H](CC3)COCC4=NC(C5=CN(N=C5)C)=C(N4CCC6=CN(N=C6)C)C7=CC=C(C=C7)C#N)=C(C=C2)CNC([C@@H]8C[C@H](CN8C([C@H](C(C)(C)C)NC(C9(CC9)F)=O)=O)O)=O
Molecular Formula
C55H66FN11O6S
Molecular Weight
1028.25
References & Citations
[1]Palaferri L, et al. Discovery of First-in-Class BAZ2A/B and BAZ2B-Selective Degraders. ACS Medicinal Chemistry Letters, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
20336121 3x 1.0µg DNA
FBXO42 CRISPRa sgRNA lentivector (set of three targets)(Human)
Sign In for Pricing
View Details 
ELI-06027h 96 Tests
Human Melanoma-derived growth regulatory protein, MIA ELISA KIT
Sign In for Pricing
View Details 
A02756-3-Dylight594 100 µg
Anti-DAP1/DAP Antibody Picoband®, Dylight594 Conjugate
Sign In for Pricing
View Details