Trans-VH 101-Thiol-C-cyclohexane-p-C-OTs
Trans-VH 101-Thiol-C-cyclohexane-p-C-OTs is the conjugate of an ligand for E3 ligase ligand and a linker, that can be used for synthesis of PROTAC degrader dBAZ2 (HY-168448) [1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC1=C(SC=N1)C2=CC=C(C=C2)CNC([C@@H]3C[C@H](CN3C([C@H](C(C)(SC[C@H]4CC[C@@H](CC4)COS(C5=CC=C(C)C=C5)(=O)=O)C)NC(C6(CC6)F)=O)=O)O)=O
Molecular Formula
C40H51FN4O7S3
Molecular Weight
815.05
References & Citations
[1]Palaferri L, et al. Discovery of First-in-Class BAZ2A/B and BAZ2B-Selective Degraders[J]. ACS Medicinal Chemistry Letters, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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