LIN28-IN-2
LIN28-IN-2 (Compound Ln268) blocks the binding of the zinc finger domain (ZKD) of Lin28 to RNA substrates, and inhibits Lin28a and Lin28b. LIN28-IN-2 inhibits the proliferation of Lin28-positive cancer cell and spheroid growth[1].
Product Specifications
UNSPSC
12352005
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Purity
99.51
Smiles
FC1=CC=C(NC(N2)=CSC2=O)C(O)=C1
Molecular Formula
C9H7FN2O2S
Molecular Weight
226.23
References & Citations
[1]Matias-Barrios VM, et al., Developing novel Lin28 inhibitors by computer aided drug design. Cell Death Discov. 2025 Jan 12;11 (1) :5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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