LIN28-IN-2

LIN28-IN-2 (Compound Ln268) blocks the binding of the zinc finger domain (ZKD) of Lin28 to RNA substrates, and inhibits Lin28a and Lin28b. LIN28-IN-2 inhibits the proliferation of Lin28-positive cancer cell and spheroid growth[1].

Product Specifications

UNSPSC

12352005

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Purity

99.51

Smiles

FC1=CC=C(NC(N2)=CSC2=O)C(O)=C1

Molecular Formula

C9H7FN2O2S

Molecular Weight

226.23

References & Citations

[1]Matias-Barrios VM, et al., Developing novel Lin28 inhibitors by computer aided drug design. Cell Death Discov. 2025 Jan 12;11 (1) :5.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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