SARS-CoV-2 3CLpro-IN-30

SARS-CoV-2 3CLpro-IN-30 (compound 29) is a potent inhibitor of SARS-CoV-2 3CL protease (SARS-CoV-2 3CLpro), with the IC50 and EC50 of 0.04 and 0.3 μM[1].

Product Specifications

UNSPSC

12352005

Target

SARS-CoV

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

N#CC1=C(C[C@@H](N)C(N[C@H](CC2=C(Cl)C=C(Cl)C=C2)C(N[C@@H](CC3=CC=C(F)C=C3)CC(NCCCC4=CC=CN=C4)=O)=O)=O)C=CC=C1

Molecular Formula

C37H37Cl2FN6O3

Molecular Weight

703.63

References & Citations

[1]Hengrui Liu, et al. Development of small molecule non-covalent coronavirus 3CL protease inhibitors from DNA-encoded chemical library screening. Nat Commun. 2025 Jan 2;16 (1) :152.