PEG (2000) -C-DMG

PEG (2000) -C-DMG is a PEGylated derivative of 1,2-Dimyristoyl-sn-glycerol (HY-128468) . PEG (2000) -C-DMG can be used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of siRNA[1].

Product Specifications

CAS Number

[1443687-74-8]

UNSPSC

12352211

Target

Liposome

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCCCCCCCCCCCC(OC(COC(NCCCOCCOC)=O)COC(CCCCCCCCCCCCC)=O)=O.[n]

Molecular Weight

2600 (Approximately)

References & Citations

[1]Hobo W, , et al. Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation. Cancer Immunol Immunother. 2013 Feb;62 (2) :285-97.