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5R (6S) -EET

5R (6S) -EET is the metabolite of Arachidonic acid (HY-109590) . 5R (6S) -EET activates the synthesis of endogenous prostaglandin (PGE2), which inhibits the Na+ absorption, increases the intracellular Ca2+, and promotes the depolarization of transmembrane voltage. 5R (6S) -EET exhibits stereoselectivity with less effectness than 5S (6R) -EET (HY-168382A) [1].

Product Specifications

CAS Number

[98103-46-9]

UNSPSC

12352211

Target

Endogenous Metabolite; Prostaglandin Receptor

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease

Field of Research

Others

Smiles

OC(CCC[C@@H]1[C@@H](O1)C/C=C\C/C=C\C/C=C\CCCCC)=O

Molecular Formula

C20H32O3

Molecular Weight

320.47

References & Citations

[1]Sakairi Y, et al., 5,6-EET inhibits ion transport in collecting duct by stimulating endogenous prostaglandin synthesis. Am J Physiol. 1995 May;268 (5 Pt 2) :F931-9.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-168382/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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