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9 (10) -Nitrooleate

9 (10) -Nitrooleate (9 (10) -Nitrated oleic acid) is a nitrated derivative of Oleic acid. 9 (10) -Nitrooleate can activate PPAR (PPARα, PPARβ/δ, and PPARγ), promoting fat formation and glucose uptake, inhibiting the function of neutrophils and platelets, and can be used in lipid metabolism and inflammation research[1].

Product Specifications

CAS Number

1092676-99-7

Product Name Alternative

9 (10) -Nitrated oleic acid

UNSPSC

12352211

Target

PPAR

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Concentration

3.05 mM * 100 μL in Ethanol

Purity

99

Smiles

OC(CCCCCCC/C([N+]([O-])=O)=C\CCCCCCCC)=O.OC(CCCCCCC/C=C([N+]([O-])=O)\CCCCCCCC)=O

Molecular Formula

C18H33NO4

Molecular Weight

327.46

References & Citations

[1]Francisco J Schopfer, et al. Fatty acid transduction of nitric oxide signaling. Nitrolinoleic acid is a hydrophobically stabilized nitric oxide donor. J Biol Chem. 2005 May 13;280 (19) :19289-97.

Shipping Conditions

Blue Ice

Storage Conditions

Solution, -20°C, 2 years

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PPARα; PPARβ/δ; PPARγ

Available Sizes

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