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BrAc-Galactose-Sar-N-Me-alanine-DM1

BrAc-Galactose-Sar-N-Me-alanine-DM1 (compound 11) is a drug-linker conjugate for ADC, which can be conjugated with the anti-TM4SF1 antibody (e.g., AGX-A07 (HY-P991187) for the synthesis of ADC[1].

Product Specifications

CAS Number

[3023560-93-9]

UNSPSC

12352005

Target

Drug-Linker Conjugates for ADC

Related Pathways

Antibody-drug Conjugate/ADC Related

Field of Research

Cancer

Smiles

C[C@@]12[C@@]([C@@H]([C@]3([H])C[C@]([C@@H](/C=C/C=C/CC4=CC(N(C(C[C@@H]2OC([C@H](C)N(C)C(CN(C)C(OCC5=CC(NC(CBr)=O)=C(C=C5)O[C@@H]6O[C@@H]([C@@H]([C@@H]([C@H]6O)O)O)CO)=O)=O)=O)=O)C)=C(C(OC)=C4)Cl)OC)(NC(O3)=O)O)C)([H])O1

Molecular Formula

C50H65BrClN5O19

Molecular Weight

1155.43

References & Citations

[1]Paul A. JAMINET, et al. Anti-tm4sf1 antibody-drug conjugates comprising cleavable linkers and methods of using same. WO2023239803A1. 2023-12-14.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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