BrAc-Galactose-Sar-N-Me-alanine-DM1
BrAc-Galactose-Sar-N-Me-alanine-DM1 (compound 11) is a drug-linker conjugate for ADC, which can be conjugated with the anti-TM4SF1 antibody (e.g., AGX-A07 (HY-P991187) for the synthesis of ADC[1].
Product Specifications
CAS Number
[3023560-93-9]
UNSPSC
12352005
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Smiles
C[C@@]12[C@@]([C@@H]([C@]3([H])C[C@]([C@@H](/C=C/C=C/CC4=CC(N(C(C[C@@H]2OC([C@H](C)N(C)C(CN(C)C(OCC5=CC(NC(CBr)=O)=C(C=C5)O[C@@H]6O[C@@H]([C@@H]([C@@H]([C@H]6O)O)O)CO)=O)=O)=O)=O)C)=C(C(OC)=C4)Cl)OC)(NC(O3)=O)O)C)([H])O1
Molecular Formula
C50H65BrClN5O19
Molecular Weight
1155.43
References & Citations
[1]Paul A. JAMINET, et al. Anti-tm4sf1 antibody-drug conjugates comprising cleavable linkers and methods of using same. WO2023239803A1. 2023-12-14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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