Mycophenolic Acid-d3 Acyl-Beta-D-glucuronide
Mycophenolic Acid-d3 Acyl-Beta-D-glucuronide is the deuterium labeled Mefuparib. Mefuparib (CVL218) is a poly ADP-ribose polymerase (PARP) inhibitor used in cancer research that exhibits potent brain penetration due to its high protein binding.
Product Specifications
UNSPSC
12352005
Target
Isotope-Labeled Compounds; PARP
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Others
Field of Research
Cancer
Smiles
OC1[C@H]([C@H]([C@@H](O[C@@H]1C(O)=O)OC(CC/C(C)=C/CC2=C(C3=C(C(C)=C2OC([2H])([2H])[2H])COC3=O)O)=O)O)O
Molecular Formula
C23H25D3O12
Molecular Weight
499.48
References & Citations
[1]Li XM, et al. Absorption, distribution, metabolism, and excretion of [14C]Mefuparib (CVL218), a novel PARP1/2 inhibitor, in rats. Cancer Chemother Pharmacol. 2022 Dec;90 (6) :499-510.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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