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Heptadecanoyl L-carnitine-d3 HCl

Heptadecanoyl L-carnitine-d3 HCl is the deuterium labeled (R, R, S) -GAT107. (R, R, S) -GAT107 is a fully agonistic positive modulator of α7 nicotinic receptors with significant biological activity. Its activity is entirely present in its (+) -isomer 1b, while (-) -isomer 1a does not affect its activity when used together. Studies have shown that (R, R, S) -GAT107 is the most potent ago-PAM for α7 nicotinic receptors currently known and has the potential for further in vivo evaluation[1].

Product Specifications

UNSPSC

12352211

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Neurological Disease

Smiles

CCCCCCCCCCCCCCCCC(O[C@H](CC(O)=O)C[N+](C)(C)C([2H])([2H])[2H])=O.Cl

Molecular Formula

C24H46D3ClNO4+

Molecular Weight

454.12

References & Citations

[1]Expeditious synthesis, enantiomeric resolution, and enantiomer functional characterization of (4- (4-bromophenyl) -3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide (4BP-TQS) : an allosteric agonist-positive allosteric modulator of α7 nicotinic acetylcholine receptors

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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