Grapiprant (Standard)
Grapiprant (Standard) is the analytical standard of Grapiprant. This product is intended for research and analytical applications. Grapiprant (CJ-023423) is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2) . Grapiprant displaces [3H]-PGE2 (1 nM) binding to dog recombinant EP4 receptor with IC50 value of 35 nM and Ki value of 24 nM. Grapiprant has the potential for osteoarthritic pain and inflammation treatment[1][2][3] .
Product Specifications
CAS Number
415903-37-6
UNSPSC
12352100
Target
Prostaglandin Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Others
Field of Research
Metabolic Disease; Endocrinology; Cancer
Smiles
O=S(C1=CC=C(C)C=C1)(NC(NCCC2=CC=C(N3C(CC)=NC4=C3C=C(C)N=C4C)C=C2)=O)=O
Molecular Formula
C26H29N5O3S
Molecular Weight
491.61
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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