Vericiguat-d6
Vericiguat-d6 (BAY1021189-d6) is deuterium labeled Vericiguat. Vericiguat (BAY1021189) is a potent, orally available and soluble guanylate cyclase stimulator.
Product Specifications
Product Name Alternative
BAY1021189-d6
UNSPSC
12352005
Target
Guanylate Cyclase; Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Others
Applications
Cancer-programmed cell death
Field of Research
Cardiovascular Disease; Cancer
Smiles
O=C(OC)NC1=C(N)N=C(C2=NN(C([2H])([2H])C3=C([2H])C([2H])=C([2H])C([2H])=C3F)C4=NC=C(F)C=C42)N=C1N
Molecular Formula
C19H10D6F2N8O2
Molecular Weight
432.42
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Follmann M, et al. Discovery of the Soluble Guanylate Cyclase Stimulator Vericiguat (BAY 1021189) for the Treatment of Chronic Heart Failure. J Med Chem. 2017 Jun 22;60 (12) :5146-5161.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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